If you’ve read my prior posts, you know that I recommend supplements and herbs for all types of uses from keeping your bones strong, to staying healthy during the winter season. So, I’m sure you were baffled if you read some recent reports on whether supplements are good for us or not.
Two recent studies have cast doubts over the usefulness of dietary supplements. One study looked at the use of vitamin and mineral supplements in 38,772 older women in the Iowa Women’s Health Study, concluding that increased use was associated with a 2.4% higher risk of mortality when compared to those that did not take supplements. Another study, The Selenium and Vitamin E Cancer Prevention Trial, found that the use of vitamin E and selenium supplements in 35,000 men slightly increased the risk of prostate cancer in the men taking vitamin E alone, and slightly increased the risk of diabetes in men taking selenium alone, but neither group’s results were statistically significant.
When headlines like these hit the newsstands, the details are in the fine print. In the women’s study, the only supplement that seemed to help reduce the risk of death was calcium. Others, like Vitamin A and D, had no effect.
When looking more in depth into the studies above, we need to consider such variables as the population studied and the supplements used. For example, the Iowa Women’s Health Study only looked at older white women, so we have to be careful to apply such conclusions to the general population.
In the men’s study, the vitamin E supplement that was used contained solely alpha-tocopherol, one of only multiple types of vitamin E produced in nature. So, can we really say that taking a synthetic, non-representative of nature vitamin E supplement would have the same effect on health as a mixed-tocopherol supplement? We have to be careful about making blanket statements on a vitamin without understanding the type that was used. In addition, the results not being statistically significant means that we really can’t draw the conclusion, and more studies need to be done.
In contrast to these reports, prior research has clearly shown scientific benefit for certain supplements.
Multiple studies have shown the following:
- Calcium and Vitamin D help prevent osteoporosis.
- Folic acid helps prevent birth defects.
- Omega-3 fatty acids help improve cellular communication, prevent cardiac arrhythmias, reduce inflammation, and lower cholesterol and blood pressure.
- Lutein and zeaxanthin help prevent age-related blindness, known as macular degeneration.
To this list, I will add vitamin B12 for vegetarians and vegans, who may not be getting enough in their diets, and patients chronically taking either a proton pump inhibitor, an acid reducer used for acid reflux, or metformin, a drug used to treat diabetes, which also causes B12 malabsorption. Patients with celiac disease may have trouble absorbing vitamins from their food, in addition to persons with malabsorption syndromes from other causes such as food intolerances and leaky gut syndrome. The elderly and alcoholics are also at higher risk for vitamin deficiencies, and will benefit from vitamin supplementation. If you feel a cold or flu coming on, research has shown that zinc can help reduce the duration of your illness.
The US Department of Health and Human Services has studied the American diet, and found that it does not always provide all the vitamins and nutrients we need. In fact, a study that analyzed seventy diets found that all subjects tested, including athletes and sedentary individuals, were short of the minimum recommended by the RDA for at least one or more key micronutrients.
So how do we sum up the parts? My recommendations are:
- Take a high-quality whole-food based multivitamin, multi-mineral formula.
- For bone health, women should take Calcium citrate 600mg twice a day.
- For its multiple health benefits, take Vitamin D3 2,000 IU daily. However, you may need up to 5,000 IU daily during the winter months if you live above the 35 degree latitude, approximately Raleigh, N.C.
- Take an EPA- and DHA-containing Omega-3, 1,000 – 2,000 mg daily for cardiovascular health.
- Discuss your special circumstances with your doctor to choose a supplement plan that best suits your individual needs. For example, if you are vegetarian or vegan, you may need extra vitamin B12.
- Finally, don’t forget, the most important first step is to eat whole, organic, non-GMO foods, preferably locally-produced, and not in excess.
 Jaako Mursu, PhD, et al. Dietary Supplements and Mortality Rate in Older Women, The Iowa Women’s Health Study. Arch Intern Med. 2011;171(18):1625-1633.
 Lippman, Scott M., MD, et al. Effect of Selenium and Vitamin E on Prostate Cancer and Other Cancers. JAMA, 2009; 301(1):39-51.
 The Lewin Group. (2006). An evidence-based study of the role of dietary supplements in helping seniors maintain their independence. Prepared for: The Dietary Supplement Education Alliance.
 Shanker, A. H. & Prasad, A. S. (1998) Zinc and immune function: the biological basis of altered resistance to infections. Am. J. Clin. Nutr. 68 (suppl. 2): 447S–463S.
 Misner, Bill. Food Alone May Not Provide Sufficient Micronutrients for Preventing Deficiency. J Int Soc Sports Nutr. 2006; 3(1): 51–55.